Saxena R P, Dogra R K, Bhattacherjee J W
Toxicol Lett. 1982 Mar;10(4):359-65. doi: 10.1016/0378-4274(82)90230-2.
The biological activity of coir fibre, coir ash and their components were investigated in vitro by measuring the haemolytic activity and macrophage cytotoxicity. In vivo studies carried out by injecting guinea pigs intratracheally with coir fibres resulted in resolving granulomas. The observed haemolytic activity and macrophage cytotoxicity was more marked with coir ash compared with coir fibres. Chemical analysis of coir ash revealed the presence of toxic chemical constituents in appreciable amounts.
通过测量溶血活性和巨噬细胞细胞毒性,在体外研究了椰壳纤维、椰壳灰及其成分的生物活性。通过气管内注射椰壳纤维对豚鼠进行的体内研究导致肉芽肿消退。与椰壳纤维相比,椰壳灰观察到的溶血活性和巨噬细胞细胞毒性更为明显。椰壳灰的化学分析显示存在大量有毒化学成分。