Autosomal phosphoglycerate kinase linked to mouse major histocompatibility complex.

The mouse autosomal locus that determines the form of phosphoglycerate kinase found only in testes is shown here to be closely linked to but not included within the major histocompatibility complex on chromosome 17. Data are presented that strongly favor the location of this locus, designated Pgk-2, distal to H-2, Qa-1, and Qa-2, and closely associated with T1a. The Pgk-2 strain distribution pattern for 103 inbred and congenic strains of mice is given. Because Pgk-2 is polymorphic among inbred strains, it should be of value in linkage studies.