Akoev G N
Brain Res. 1982 May 13;239(2):391-9. doi: 10.1016/0006-8993(82)90517-0.
The effect of altering extracellular Ca2+ and Mg2+ levels on electrical properties of Pacinian corpuscles of adult cat has been examined. High Mg2+ solution (5--15 mM) increased the excitability of the receptors and the amplitude of the receptor potential. Ca2+-free EDTA solution caused an increase in the amplitude of the receptor potential in the first 60 min and then its decrease. Mg2+ ions slow down or prevent the depressant effect of the Ca2+ lack on the receptor potential. The phase of the receptor potential amplitude increase in Ca2+-free media was reversibly blocked by tetraethylammonium ions. Treatment with 2,4-dinitrophenol produced a transient increase in the receptor potential amplitude. The threshold of the mechanosensitive receptor membrane was unaffected in Ca2+-free or Mg2+-rich solution. The results suggest that divalent cations are not directly involved in the process of mechanoelectric transformation in Pacinian corpuscles.
研究了改变细胞外Ca2+和Mg2+水平对成年猫环层小体电特性的影响。高Mg2+溶液（5 - 15 mM）增加了感受器的兴奋性和感受器电位的幅度。无Ca2+的EDTA溶液在最初60分钟内使感受器电位幅度增加，随后降低。Mg2+离子减缓或阻止了Ca2+缺乏对感受器电位的抑制作用。在无Ca2+介质中感受器电位幅度增加的阶段被四乙铵离子可逆性阻断。用2,4 - 二硝基苯酚处理使感受器电位幅度短暂增加。在无Ca2+或富含Mg2+的溶液中，机械敏感感受器膜的阈值未受影响。结果表明二价阳离子不直接参与环层小体的机电转换过程。
