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[尾状核和下丘脑后部中神经降压素受体的存在]

[Existence of neurotensin receptors in the caudate nucleus and posterior hypothalamus].

作者信息

Suvorov N F, Klimov P K, Iakimovskii A F, Fokina A A, Barashkova G M

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1982 May;68(5):627-31.

PMID:6284558
Abstract

Chronic experiments in dogs revealed that administration of neurotensin (3 and 10 mkg in 1.5 mkl) into the caudate nucleus altered the parameters of conditioned and unconditioned food reflexes: shortened the latency by 31% and augmented the reflexes by 56%. The microapplication of neurotensin in the same dosage into the posterior hypothalamus increased the stomach secretory function induced by histamine administration. The caudate nucleus and the hypothalamus seem to contain cells which have the receptors for neurotensin and take part in the mechanisms of conditioning and central influences on the digestive system's organs.

摘要

对狗进行的慢性实验表明,向尾状核注射神经降压素(1.5微升中含3微克和10微克)会改变条件性和非条件性食物反射的参数:使潜伏期缩短31%,并使反射增强56%。以相同剂量将神经降压素微量注射到下丘脑后部,会增强由组胺给药诱导的胃分泌功能。尾状核和下丘脑似乎含有具有神经降压素受体的细胞,并参与条件反射机制以及对消化系统器官的中枢影响机制。

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