Mees K, Wolf H, Roggendorf M
Laryngol Rhinol Otol (Stuttg). 1981 Dec;60(12):609-11.
In a prospective study paired sera of 14 patients suffering from Bell's palsy were examined for antibodies against Varicella-zoster Virus (VZV), Herpes-simplex Virus (HSV), Cytomegalovirus (CMV) and Epstein-Barr Virus (EBV). For determination of antibodies against VZV, HSV and CMV an enzyme-linked immunosorbent assay was carried out. Indirect immunofluorescence was carried out to determine antibodies against EBV. Serum samples were taken within 5 days of Bell's palsy having been diagnosed and were compared with further serum samples taken 4 weeks later. No evidence of significant differences between the antibody titers of the paired sera was found. The viral etiology of Bell's palsy due to an exogenous infection or by activation of a latent infection seems unlikely.
在一项前瞻性研究中，检测了14例贝尔氏面瘫患者的配对血清，以寻找抗水痘-带状疱疹病毒（VZV）、单纯疱疹病毒（HSV）、巨细胞病毒（CMV）和爱泼斯坦-巴尔病毒（EBV）的抗体。采用酶联免疫吸附测定法检测抗VZV、HSV和CMV的抗体。采用间接免疫荧光法检测抗EBV的抗体。在贝尔氏面瘫确诊后5天内采集血清样本，并与4周后采集的进一步血清样本进行比较。未发现配对血清抗体滴度之间存在显著差异的证据。由外源性感染或潜伏感染激活导致贝尔氏面瘫的病毒病因似乎不太可能。
