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[异丙肾上腺素支气管扩张对各种临床类型支气管哮喘患者氧分压的影响]

[Effects of isoprenaline bronchodilation on the partial pressure of oxygen in various clinical forms of bronchial asthma].

作者信息

Carpentiere G, Marino S

出版信息

Minerva Med. 1978 Feb 4;69(6):379-81.

PMID:628523
Abstract

Blood gas disturbances noted in recent asthma were fully corrected with 1% isoprenalin aerosol, though changes in PaO2 were usually unobtainable in patients with chronic bronchopneumopathic obstruction. Simultaneous administration of 70% hyperoxygenated air via an intermittent positive pressure respirator led to a significant increase in this parameter, but was rarely followed by normalisation of the blood gas picture. It is considered that this finding is attributable to increased anatomical shunt at the alveolocapillary level.

摘要

近期哮喘中所观察到的血气紊乱,使用1%异丙肾上腺素气雾剂可完全纠正,不过在慢性支气管肺炎性阻塞患者中,通常无法测得动脉血氧分压(PaO2)的变化。通过间歇正压呼吸器同时给予70%的高氧空气,可使该参数显著升高,但血气状况很少能恢复正常。据认为,这一发现归因于肺泡毛细血管水平解剖分流增加。

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