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用于胃黏膜99m锝高锝酸盐显像的氨甲酰胃泌素。

Amogastrin for the 99mTc-pertechnetate imaging of the gastric mucosa.

作者信息

Okuyama S, Mishina H

出版信息

Radioisotopes. 1982 Mar;31(3):141-4. doi: 10.3769/radioisotopes.31.3_141.

DOI:10.3769/radioisotopes.31.3_141
PMID:6285422
Abstract

Most of the gastric diseases seat in the mucosa, and the present investigation was undertaken in order to see if amogastrin, a synthetic tetrapeptide, was capable of enhancing gastric accretion of intravenous 99mTc pertechnetate in man as well as in the rabbit. Improvement of gastric scintigraphy was achievable with a pretreatment of the agent by increasing the gastric accretion and reducing the background radioactivity in the liver and small intestinum.

摘要

大多数胃部疾病位于黏膜层,本次研究旨在探究一种合成四肽——氨基胃泌素是否能够增强人体及兔子静脉注射高锝[99mTc]酸盐后的胃部摄取。通过增加胃部摄取并降低肝脏和小肠的本底放射性,对该药物进行预处理可实现胃闪烁显像的改善。

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