Sfakianakis G N, Conway J J
J Nucl Med. 1981 Jul;22(7):647-54.
Ten years of clinical experience with pertechnetate (Tc-99m) scintigraphy has proven its validity for the diagnosis of ectopic gastric mucosa in bleeding Meckel's diverticulum and other congenital anomalies. Careful patient preparation and a standardized technique based on sequential gamma imaging has resulted in an overall sensitivity of 85%. Experience in differentiating "nonspecific" accumulations of pertechnetate from true ectopic gastric mucosa had increased the specificity to 95%. When we consider all the studies reported (954) with a surgical or clinical diagnosis, the accuracy of the method is calculated at 98%. When only surgically proven cases are analyzed, the calculated accuracy is 90%. Pertechnetate excretion by the mucoid cells of gastric mucosa is the basis of this test. The effect of drugs and hormones on the test has been studied in animals and in patients. The findings suggest that an improvement can be achieved by the use of cimetidine, pentagastrin, or glucagon.
十年的高锝酸盐（Tc-99m）闪烁扫描临床经验已证明其在诊断出血性梅克尔憩室及其他先天性异常中的异位胃黏膜方面的有效性。精心的患者准备以及基于连续伽马成像的标准化技术使总体敏感性达到了85%。区分高锝酸盐“非特异性”聚集与真正异位胃黏膜的经验已将特异性提高到95%。当我们考虑所有报告的（954例）经手术或临床诊断的研究时，该方法的准确性计算为98%。仅分析经手术证实的病例时，计算出准确性为90%。胃黏膜黏液细胞排泄高锝酸盐是该检查的基础。已在动物和患者中研究了药物和激素对该检查的影响。研究结果表明，使用西咪替丁、五肽胃泌素或胰高血糖素可实现改善。
