Plesneva S A
Ukr Biokhim Zh (1978). 1982 May-Jun;54(3):264-9.
Sodium metavanadate (10(-4)-10(-6) M) stimulates the activity of adenylate cyclase and decreases the activity of Na+, K+-ATRase and 5'-nucleotidase in the sarcolemma fraction of chicken skeletal muscles at the embryonal and postembryonal developmental stages. Under conditions of a combined action of vanadate and guanylic nucleotides on the adenylate cyclase activity their effects are found to be potentiated. Epinephrine in vitro removes an inhibitory influence of vanadate on Na+, K+-ATPase from the third week of twe embryonal period. The restoring effect of epinephrine is blocked by propranol--a beta-adrenoblocker.
偏钒酸钠（10⁻⁴ - 10⁻⁶ M）在胚胎期和胚胎后期发育阶段，可刺激鸡骨骼肌肌膜部分的腺苷酸环化酶活性，并降低Na⁺、K⁺ - ATP酶和5'-核苷酸酶的活性。在钒酸盐和鸟苷酸对腺苷酸环化酶活性的联合作用条件下，发现它们的作用具有增强效果。在胚胎期第三周开始，肾上腺素在体外可消除钒酸盐对Na⁺、K⁺ - ATP酶的抑制作用。肾上腺素的这种恢复作用被β - 肾上腺素能阻滞剂普萘洛尔所阻断。
