[兔骨骼肌肌膜腺苷酸环化酶的特性]
[Properties of adenylate cyclase of rabbit skeletal muscle sarcolemma].
作者信息
Dmitrenko N P
出版信息
Ukr Biokhim Zh (1978). 1978 Sep-Oct;50(5):607-11.
PMID:103269
Abstract
The sarcolemma fraction with a considerable adenylate cyclase activity sensitive to adrenalin is isolated from the rabbit skeletal muscles. Some its properties are established: pH-optimum of the activity, stability in storage and resistance to the effect of different pH and temperature. Acetylcholine and ruthenium red do not affect the adenylate cyclase activity of the sarcolemma. EGTA activates and Ca2+ inhibits it having no effect on sensitivity to adrenalin.
摘要
从兔骨骼肌中分离出具有相当高的对肾上腺素敏感的腺苷酸环化酶活性的肌膜部分。确定了其一些特性：活性的最适pH值、储存稳定性以及对不同pH值和温度影响的抗性。乙酰胆碱和钌红不影响肌膜的腺苷酸环化酶活性。乙二醇双四乙酸（EGTA）激活该酶，而Ca2+抑制该酶，且对其对肾上腺素的敏感性无影响。
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