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[小型近交鸡品系对劳氏肉瘤病毒感染的易感性分析]

[Analysis of the susceptibility of the Minor inbred chicken strain to Rous sarcoma virus infection].

作者信息

Korec E, Klozánek I

出版信息

Vet Med (Praha). 1982 Mar;27(3):175-83.

PMID:6285582
Abstract

The sensitivity and resistance of the Minor hen inbred line to two antigenic subgroups of the Rous sarcoma virus were determined by the method of the infection of chorioallantoic membranes. The Minor line is sensitive to infection with the virus of the antigenic B subgroup and, as demonstrated by the testing of the interline hybrids of F1 and B1 generations, the birds of the Minor line are dominant homozygotes of genotype bsbs. The testing with the virus of antigenic A subgroup revealed a heterogeneity of the inbred population as to sensitivity and resistance. A formula was derived for the determination of the frequency of the dominant allele as determining sensitivity.

摘要

采用绒毛尿囊膜感染法测定了米诺尔近交系对劳氏肉瘤病毒两个抗原亚组的敏感性和抗性。米诺尔品系对B抗原亚组病毒的感染敏感,并且如F1和B1代品系间杂种的测试所示,米诺尔品系的鸡是基因型bsbs的显性纯合子。用A抗原亚组病毒进行的测试表明,近交群体在敏感性和抗性方面存在异质性。推导了一个公式,用于确定决定敏感性的显性等位基因的频率。

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