Schaeffer H J
Am J Med. 1982 Jul 20;73(1A):4-6. doi: 10.1016/0002-9343(82)90054-7.
Most antiviral agents with activity against the herpes group of viruses belong to a class of compounds known as nucleosides. Recently, an acyclic analog of a natural nucleoside has been found to have high activity against the herpes virus. This compound, called generically acyclovir, is 9-(hydroxymethyl)guanine. Its spectrum of antiviral activity is described.
大多数对疱疹病毒群有活性的抗病毒剂属于一类称为核苷的化合物。最近,一种天然核苷的无环类似物被发现对疱疹病毒具有高活性。这种化合物,通用名为阿昔洛韦,是9-(羟甲基)鸟嘌呤。描述了其抗病毒活性谱。