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阿昔洛韦的化学性质与活性谱。

Acyclovir chemistry and spectrum of activity.

作者信息

Schaeffer H J

出版信息

Am J Med. 1982 Jul 20;73(1A):4-6. doi: 10.1016/0002-9343(82)90054-7.

Abstract

Most antiviral agents with activity against the herpes group of viruses belong to a class of compounds known as nucleosides. Recently, an acyclic analog of a natural nucleoside has been found to have high activity against the herpes virus. This compound, called generically acyclovir, is 9-(hydroxymethyl)guanine. Its spectrum of antiviral activity is described.

摘要

大多数对疱疹病毒群有活性的抗病毒剂属于一类称为核苷的化合物。最近,一种天然核苷的无环类似物被发现对疱疹病毒具有高活性。这种化合物,通用名为阿昔洛韦,是9-(羟甲基)鸟嘌呤。描述了其抗病毒活性谱。

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