Walmsley J A, Pinnavaia T J
Biophys J. 1982 Jun;38(3):315-8. doi: 10.1016/s0006-3495(82)84564-5.
The stability of the 1:1 complex of sodium ion with the dianion of guanosine 5'-monophosphate has been determined by means of a potentiometric titration employing a specific ion electrode. The stability constant for the reaction Na(+) + 5'-GMP(2-) Na(5'-GMP)(-) was found to be 2.85 +/- 0.36 M(-1) at 5 degrees C and an ionic strength of 1.1 +/- 0.1 M. Although 5'-GMP forms ordered self-structures at high concentration in the presence of sodium ions, in dilute solution and at low sodium ion concentrations the Na(+) binding is weak and typical of that for other nucleotides.
通过使用特定离子电极的电位滴定法测定了钠离子与5'-鸟苷单磷酸二价阴离子1:1配合物的稳定性。发现在5℃和离子强度为1.1±0.1M的条件下，反应Na(+) + 5'-GMP(2-)⇌Na(5'-GMP)(-)的稳定常数为2.85±0.36M⁻¹。尽管在高浓度钠离子存在下5'-GMP会形成有序的自组装结构，但在稀溶液和低钠离子浓度下，Na(+)的结合较弱，这是其他核苷酸的典型特征。
