Croissant O, Testanière V, Orth G
C R Seances Acad Sci III. 1982 Mar 22;294(12):581-6.
Three regions of partial homology have been detected between the genomes of human papillomavirus 1 a (HPV-1 a) and bovine papillomavirus 1 (BPV-1) by electron microscope analysis of heteroduplex molecules. These regions contain about 25% of non-homologous bases and represent 13% of the genome length. They have been mapped on the viral DNAs. This allowed a reciprocal orientation of the physical maps of the two genomes. Two regions are located in the middle of the transforming fragment of BPV-1 DNA and the third, at at diametrically opposite position, falls into the region of the genome coding most probably for a viral structural protein.
通过对异源双链分子的电子显微镜分析，在人乳头瘤病毒1a（HPV-1a）和牛乳头瘤病毒1（BPV-1）的基因组之间检测到三个部分同源区域。这些区域含有约25%的非同源碱基，占基因组长度的13%。它们已定位在病毒DNA上。这使得两个基因组的物理图谱能够相互对应。两个区域位于BPV-1 DNA转化片段的中间，第三个区域位于完全相反的位置，很可能落入基因组中编码病毒结构蛋白的区域。
