[Detection and mapping of conserved nucleotidic sequences between the genomes of human papillomavirus 1 a and bovine papillomavirus 1 by electron microscope heteroduplex analysis (author's transl)].

Three regions of partial homology have been detected between the genomes of human papillomavirus 1 a (HPV-1 a) and bovine papillomavirus 1 (BPV-1) by electron microscope analysis of heteroduplex molecules. These regions contain about 25% of non-homologous bases and represent 13% of the genome length. They have been mapped on the viral DNAs. This allowed a reciprocal orientation of the physical maps of the two genomes. Two regions are located in the middle of the transforming fragment of BPV-1 DNA and the third, at at diametrically opposite position, falls into the region of the genome coding most probably for a viral structural protein.