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来自莫里斯肝癌9121细胞核的与染色质结合的酶催化的核苷三磷酸合成。

Nucleoside triphosphate syntheses by chromatin bound enzymes from Morris hepatoma 9121 nuclei.

作者信息

Lenger K

出版信息

Int J Biochem. 1982;14(7):673-7. doi: 10.1016/0020-711x(82)90053-2.

Abstract
  1. Enzymatic syntheses of deoxyribo- and ribonucleoside triphosphates were observed with purified, chromatin bound enzyme C from Morris Hepatoma 9121 nuclei. 2. Intermediate substrates were nucleoside mono- and diphosphates for enzyme C. 3. The three phosphate residues of ATP serving as energy-rich phosphate donor were successively transferred to a nucleoside substrate by enzyme C.
摘要
  1. 用从莫里斯肝癌9121细胞核中纯化的、与染色质结合的C酶观察到了脱氧核糖核苷三磷酸和核糖核苷三磷酸的酶促合成。2. 酶C的中间底物是核苷单磷酸和二磷酸。3. 作为富能磷酸供体的ATP的三个磷酸残基被酶C依次转移到核苷底物上。

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