从斯卡查德图得出的受体位点数量：事实与幻想
Numbers of receptor sites from Scatchard graphs: facts and fantasies.
作者信息
Klotz I M
出版信息
Science. 1982 Sep 24;217(4566):1247-9. doi: 10.1126/science.6287580.
PMID:6287580
Abstract
Data for ligand and receptor binding presented in the format of a Scatchard graph are compared with the same data shown as bound ligand plotted against the logarithm of free ligand. From this comparison it is apparent that extrapolations in the Scatchard graph to yield total number of receptor sites are generally not correct.
摘要
以Scatchard图形式呈现的配体与受体结合数据，与以结合配体对游离配体对数作图展示的相同数据进行了比较。从该比较中可以明显看出，在Scatchard图中用于得出受体位点总数的外推法通常是不正确的。
Zotero 插件