纳洛酮对苯环己哌啶体温调节作用的拮抗作用。
Naloxone antagonism of the thermoregulatory effects of phencyclidine.
作者信息
Glick S D, Guido R A
出版信息
Science. 1982 Sep 24;217(4566):1272-3. doi: 10.1126/science.6287581.
PMID:6287581
Abstract
Phencyclidine elicits hyperthermia at low doses and hypothermia at high doses in rats. Naloxone antagonizes both effects. Phencyclidine's effects on thermo-regulation are probably mediated by an interaction with a mu opiate receptor.
摘要
在大鼠中，苯环利定在低剂量时会引起体温过高，而在高剂量时会引起体温过低。纳洛酮可拮抗这两种效应。苯环利定对体温调节的作用可能是通过与μ阿片受体相互作用介导的。
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