Müller M, Fehm H L, Homoki J, Teller W M
Dtsch Med Wochenschr. 1982 Sep 10;107(36):1353-6. doi: 10.1055/s-2008-1070129.
Synthetic 1-24adrenocorticotrophin (tetracosactid, Synacthen) is used in clinical medicine for diagnostic and therapeutic purposes. Side effects may occur due to unphysiological stimulation of endogenous adrenocortical hormone production. Allergic reactions to tetracosactid are rare. Anaphylactic shock leading to death was observed after intravenous injection of tetracosactid in a 14-year-old girl with bronchial asthma. Adrenocorticotrophin antibodies could be demonstrated after death in serum and ascitic fluid using the double antibody method.
合成的1-24促肾上腺皮质激素（二十四肽促皮质素，新促皮质素）在临床医学中用于诊断和治疗目的。由于对内源性肾上腺皮质激素产生的非生理性刺激，可能会出现副作用。对二十四肽促皮质素的过敏反应很少见。在一名患有支气管哮喘的14岁女孩静脉注射二十四肽促皮质素后，观察到过敏性休克导致死亡。死后使用双抗体法在血清和腹水中检测到促肾上腺皮质激素抗体。
