人淋巴细胞对EB病毒感染易感性的简易检测方法。
Simple assay method for susceptibility of human lymphocytes to Epstein-Barr virus infection.
作者信息
Takada K, Osato T
出版信息
Intervirology. 1982;18(1-2):87-91. doi: 10.1159/000149308.
On the basis of the sequential early events induced by Epstein-Barr virus (EBV), the infectivity of human lymphocytes to EBV was quantified as a plateau value of the maximum nuclear antigen (EBNA) synthesis preceding cellular DNA synthesis. The frequency of EBV-infectible cells was an average of 7.6% of unfractionated umbilical cord lymphocytes and was 4.9% in the counterparts from human adults. In the B-cell-enriched populations, the average plateau values were 29.2% in umbilical cord and 15.5% in adult samples. This method is simple and applicable for quantitative assay of the sensitivity to EBV infection of a given lymphocyte preparation.
基于爱泼斯坦-巴尔病毒（EBV）诱导的一系列早期事件，人淋巴细胞对EBV的感染性被量化为细胞DNA合成之前最大核抗原（EBNA）合成的平台值。EBV可感染细胞的频率在未分级的脐带淋巴细胞中平均为7.6%，在成人对应样本中为4.9%。在富含B细胞的群体中，脐带血样本的平均平台值为29.2%，成人样本为15.5%。该方法简单，适用于定量测定给定淋巴细胞制剂对EBV感染的敏感性。
Zotero 插件