Dax E M, Partilla J S
Mol Pharmacol. 1982 Jul;22(1):5-7.
The binding of [3H]dihydroalprenolol to adipocyte membranes may be displaced not only from beta-adrenergic receptors but also nonstereospecifically from other membrane compartments by beta-adrenergic and other adrenergic agents. The EC50 of this nonstereospecific displaceable binding is directly related to the liposolubility (n-octanol:water partition coefficient) of the displacing ligand.
[3H]二氢烯丙洛尔与脂肪细胞膜的结合不仅可从β-肾上腺素能受体上被取代，还可被β-肾上腺素能药物和其他肾上腺素能药物非立体特异性地从其他膜区室上取代。这种非立体特异性可取代结合的半数有效浓度（EC50）与取代配体的脂溶性（正辛醇：水分配系数）直接相关。
