[Measurement of post-irradiation population kinetics using single-cell cytophotometry combined with double-labeling autoradiography: model investigations into a diploid Ehrlich ascites tumor after 475 rd X-irradiation (author's transl)].

A technique for in vivo determination of the population kinetics in tumors following irradiation is reported in this paper. Using the model of a diploid Ehrlich ascites tumor (EAT-dipl), the migration of cells from different subpopulations was followed up through the generation cycle. The measurability of post-irradiation growth kinetics in different subpopulations is emphasized with regard to its importance for practical application with combination treatments or possibility for the problem of dose-time relations. The individual results obtained after 475 rd are presented in detail.