Diamond L S
Rev Infect Dis. 1982 Jul-Aug;4(4):843-50. doi: 10.1093/4.4.843.
Studies on the role of nutrition in amebiasis in humans and experimental animals are meager. Some reports suggest that malnutrition of the host increases the incidence of infection and potentiates the severity of the disease. Others suggest that malnutrition protects the host against invasion. A few reports indicate that dietary regimens can alleviate symptoms and even eradicate the parasite. Others doubt a correlation between diet and rate of infection or disease manifestations. The problem is complex because the ameba is influenced by its own diet, which in turn depends on the host's diet, the bacterial flora of the gut, and coexisting infections. The host is variously altered by dietary depletions and supplementations, which affect susceptibility and resistance, and by the presence of other disease conditions. Carefully designed and executed studies of infections in humans and experimental animals, combined with studies in vitro of the nutritional requirements and physiology of the parasite, are needed for definition of the influence of host nutrition in amebiasis.
关于营养在人类和实验动物阿米巴病中作用的研究很少。一些报告表明，宿主营养不良会增加感染发生率并加重疾病严重程度。另一些报告则表明，营养不良可保护宿主免受侵袭。一些报告指出，饮食方案可缓解症状甚至根除寄生虫。还有一些报告对饮食与感染率或疾病表现之间的相关性表示怀疑。这个问题很复杂，因为阿米巴受到自身饮食的影响，而自身饮食又取决于宿主饮食、肠道菌群和并存感染。饮食的消耗和补充会以各种方式改变宿主，影响易感性和抵抗力，同时其他疾病状况的存在也会产生影响。需要对人类和实验动物感染进行精心设计和实施的研究，并结合对寄生虫营养需求和生理学的体外研究，以确定宿主营养在阿米巴病中的影响。
