Reed S L
Division of Infectious Diseases, UCSD Medical Center, California 92103-8416.
Clin Infect Dis. 1992 Feb;14(2):385-93. doi: 10.1093/clinids/14.2.385.
Although amebiasis is often considered a disease of developing countries, it is an important public health problem throughout the world. At least 90% of infected patients are asymptomatic, but the remainder may present with clinical syndromes ranging from frank dysentery to abscesses of the liver, lungs, or brain. The most common challenge for physicians in developed countries is treating infection due to Entamoeba histolytica in an asymptomatic patient or determining its clinical significance in a patient with AIDS who has diarrhea. In light of recent improvements in diagnosis and therapy, the protean clinical manifestations of amebic infection are reviewed along with the indications for therapy. Advances in research that may directly affect our management of amebiasis in the near future are highlighted.
尽管阿米巴病通常被认为是发展中国家的疾病，但它是全球一个重要的公共卫生问题。至少90%的感染患者无症状，但其余患者可能出现从明显痢疾到肝、肺或脑脓肿等临床综合征。发达国家医生面临的最常见挑战是治疗无症状患者的溶组织内阿米巴感染，或确定其在患有腹泻的艾滋病患者中的临床意义。鉴于近期诊断和治疗方面的进展，本文对阿米巴感染的多种临床表现以及治疗指征进行了综述。重点介绍了可能在不久的将来直接影响我们对阿米巴病管理的研究进展。
