婴儿肾母细胞瘤的治疗结果。意大利，1970 - 1979年。

The outcome of Wilms' tumor in infants. Italy 1970-79.

作者信息

Pastore G, Cordero di Montezemolo L, Brach del Prever A, Bartolozzi G, Carli M, Castello M, Ceci A, Fossati-Bellani F, Guazzelli C, Lo Curto M, Madon E, Marchi A, Massolo F, Mori P G, Paolucci G, Pianca C, Rosati M, Tamaro P

出版信息

Tumori. 1982 Apr 30;68(2):133-6. doi: 10.1177/030089168206800206.

DOI:10.1177/030089168206800206

PMID:6289502

Abstract

Thirty-four infants under 1 year of age with Wilms' tumor were diagnosed and treated in 14 Italian pediatric oncology units during 1970-79. The 3-year survival rates decreased with higher group unilateral tumors: 95% in group I Wilms' tumor, 75% in group II and 20% in group III. The survival rates for children with group I and II Wilms' tumor were similar for those who were treated with surgery and chemotherapy and those who also received postoperative radiotherapy. During 1975-79 fewer patients with group I Wilms' tumor received radiotherapy (1 of 11) than during 1970-74 (4 of 6, p less than 0.05). All these children are alive at this writing.

摘要

1970年至1979年期间，14个意大利儿科肿瘤治疗单位诊断并治疗了34名1岁以下患有肾母细胞瘤的婴儿。随着单侧肿瘤分组级别升高，3年生存率下降：I组肾母细胞瘤为95%，II组为75%，III组为20%。接受手术和化疗的I组和II组肾母细胞瘤患儿与那些还接受术后放疗的患儿生存率相似。1975年至1979年期间，接受放疗的I组肾母细胞瘤患者（11例中的1例）比1970年至1974年期间（6例中的4例，p<0.05）少。撰写本文时，所有这些儿童均存活。