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卵巢男性母细胞瘤中的神经激素肽和嗜银细胞

Neurohormonal peptides and argyrophil cells in an androblastoma of the ovary.

作者信息

Sporrong B, Clase L, Ljungberg O, Wadstein C

出版信息

Virchows Arch A Pathol Anat Histol. 1982;396(2):239-46. doi: 10.1007/BF00431245.

DOI:10.1007/BF00431245
PMID:6289514
Abstract

An ovarian epithelial tumour is described with a compound histological structure containing features of an androblastoma with well differentiated Sertoli-Leydig cell structures and features resembling a carcinoid tumour. Scattered argyrophil cells were demonstrated in both components of the tumour. Neurohormonal peptides were found immunocytochemically in a minor fraction of the argyrophil cells. These included pancreatic polypeptide (PP), glucagon/enteroglucagon and enkephalin. These findings indicate a high degree of multipotentiality of the progenitor cells of the neoplasm.

摘要

描述了一种卵巢上皮性肿瘤,其具有复合组织学结构,包含具有分化良好的支持-间质细胞结构的男性母细胞瘤特征以及类似类癌肿瘤的特征。在肿瘤的两个成分中均发现散在的嗜银细胞。通过免疫细胞化学方法在一小部分嗜银细胞中发现了神经激素肽。这些包括胰多肽(PP)、胰高血糖素/肠胰高血糖素和脑啡肽。这些发现表明该肿瘤祖细胞具有高度的多能性。

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本文引用的文献

1
Composite mucinous ovarian neoplasms associated with Sertoli-Leydig and carcinoid tumors.与支持-间质细胞瘤和类癌肿瘤相关的复合性黏液性卵巢肿瘤。
Cancer. 1981 Apr 15;47(8):2044-52. doi: 10.1002/1097-0142(19810415)47:8<2044::aid-cncr2820470824>3.0.co;2-b.
2
Neurohormonal peptide immunoreactive cells in mucinous cystadenomas and cystadenocarcinomas of the ovary.卵巢黏液性囊腺瘤和囊腺癌中的神经激素肽免疫反应性细胞。
Virchows Arch A Pathol Anat Histol. 1981;392(3):271-80. doi: 10.1007/BF02155665.
3
Androblastoma of the ovary with heterotopic elements.
J Pathol. 1973 Mar;109(3):267-70. doi: 10.1002/path.1711090314.
4
Primary trabecular carcinoid of the ovary.卵巢原发性小梁类癌
Obstet Gynecol. 1977 Feb;49(2):202-7.