Permiakov N K, Titova G P, Senianskaia N L, Khvatov V B, Platonova T K
Arkh Patol. 1982;44(6):31-6.
The effect of a new thrombolytic preparation, plasmakinase, on experimental coagulates and thrombi was studied morphologically. Histological and electron microscopic studies revealed changes in the structure of fibrin fibers in the form of separation of fibers into individual protofibrils and subsequent degradation into globular particles. There were disorders in the fibrin association with blood cells, washing out of partially hemolyzed red blood cells into the bloodstream, decrease in the size of thrombi and restoration of the vessel lumen.
对一种新型溶栓制剂——血浆激酶对实验性凝血块和血栓的作用进行了形态学研究。组织学和电子显微镜研究显示，纤维蛋白纤维结构发生变化，表现为纤维分离成单个原纤维，随后降解为球状颗粒。纤维蛋白与血细胞的结合出现紊乱，部分溶血的红细胞被冲入血流，血栓尺寸减小，血管腔恢复。
