Carollo C, Marin G, Scanarini M, Ori C, Drigo P, Casara G L, Laverda A M
Childs Brain. 1982 Sep-Oct;9(5):347-53. doi: 10.1159/000120071.
Computed tomography of 8 cases with West's syndrome before, during and after ACTH treatment are reported. The scans, performed at the third week of therapy, showed consistent widening of the sulci, cisterns and ventricles in all the patients. Of these, 2 patients underwent ICP monitoring which showed higher than normal values. A return to the normal ICP values in association with the disappearance of the CT findings was observed in both cases. It is concluded that widening of the sulci, cisterns and ventricles are not findings of atrophy, but a condition of initial communicating hydrocephalus, which is in accordance with the hypotheses of Riikonen and Lyen.
报告了8例韦斯特综合征患者在促肾上腺皮质激素（ACTH）治疗前、治疗期间和治疗后的计算机断层扫描结果。在治疗第三周进行的扫描显示，所有患者的脑沟、脑池和脑室均持续增宽。其中2例患者进行了颅内压（ICP）监测，结果显示高于正常值。在这两例患者中，均观察到颅内压值恢复正常，同时CT表现消失。结论是，脑沟、脑池和脑室增宽并非萎缩的表现，而是初期交通性脑积水的一种情况，这与里科宁和莱恩的假说相符。
