[异卡波铵滴眼液局部应用对神经肌肉传递的影响]

[Influence of local application of isoptomax eye drops on neuromuscular transmission].

作者信息

Koenig A, Ohrloff C

出版信息

Klin Monbl Augenheilkd. 1981 Aug;179(2):109-12. doi: 10.1055/s-2008-1057273.

DOI:10.1055/s-2008-1057273

Abstract

The muscle-relaxing effect of antibiotics, particularly that of aminoglycosides and polymyxins after oral, intravenous, intramuscular and local application is described. After local application of Isoptomax eye drops, one patient suffered from relaxation of the muscular system of the neck and throat. The phenomenon did not recede until several hours after therapy was discontinued. The mechanism of action is described and a possible treatment discussed with reference to the relevant literature.

摘要

本文描述了抗生素的肌肉松弛作用，尤其是氨基糖苷类和多粘菌素在口服、静脉注射、肌肉注射及局部应用后的肌肉松弛作用。局部应用异帕托品滴眼液后，有1例患者出现颈部和咽喉部肌肉系统松弛。该现象直到治疗停止数小时后才消退。文中描述了其作用机制，并参考相关文献讨论了可能的治疗方法。