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[脑血管疾病中的血清酶谱]

[Blood serum enzymatic spectrum in vascular diseases of the brain].

作者信息

Barsukvoa M D, Drozdova G A

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1978;78(1):61-5.

PMID:629145
Abstract

The presentation deals with the enzymatic spectrum of the blood serum (aminotransferase-glutamino-pyruvic and glutamino-oxaloacetic acid, sera cholinesterase, histidase, acid alkaline phosphatase) in 100 patients with transient disorders of cerebral circulation in the form of ischemic and hemorrhagic strokes. These disorders of circulation appeared on the background [corrected] of atherosclerosis and hypertensive disease or in other combination along with vasculitis of a different etiology. The most significant were changes of histidase and acid phosphatase activity and an inhibition of cholinesterase activity in ischemic and hemorrhagic strokes with expressed focal disorders of cerebral circulation. In an improvement of the clinical state following medicative therapy there was a normalization of these indices. The only exclusion was histidase the content of which in some cases remained cunhanged.

摘要

本报告研究了100例以缺血性和出血性中风形式出现的短暂性脑循环障碍患者血清中的酶谱(氨基转移酶 - 谷氨酰胺 - 丙酮酸和谷氨酰胺 - 草酰乙酸、血清胆碱酯酶、组氨酸酶、酸性碱性磷酸酶)。这些循环障碍出现在动脉粥样硬化和高血压疾病背景下,或与其他不同病因的血管炎合并出现。在伴有明显局灶性脑循环障碍的缺血性和出血性中风中,最显著的变化是组氨酸酶和酸性磷酸酶活性的改变以及胆碱酯酶活性的抑制。药物治疗后临床状态改善时,这些指标恢复正常。唯一的例外是组氨酸酶,其含量在某些情况下保持不变。

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