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肾母细胞瘤:腔静脉侵犯的处理方法

Wilms' tumor: an approach to vena caval intrusion.

作者信息

Clayman R V, Sheldon C A, Gonzales R

出版信息

Prog Pediatr Surg. 1982;15:285-305.

PMID:6293000
Abstract

Wilms' tumor invades the renal vein in 12% of patients and extends into the inferior vena cava in another 6%. In a few cases, the tumor propagates into the right side of the heart. Since patients with Wilms' tumor seldom require renal arteriography, and because vena cava involvement may be silent, venous invasion may go undetected until the time of radical nephrectomy. A preoperative vena cavogram is recommended, and if a thrombus is found, a right heart angiogram is needed to determine the superior extent of thrombus. An understanding of the collateral venous circulation of the kidneys and of the physiological effects of malignant or iatrogenic obstruction of the inferior vena cava are essential to formulating the operative approach. Various operative maneuvers, intraoperative studies, and surgical aids (including cardiopulmonary bypass and hypothermia) have made forms of intracaval Wilms' tumor amenable to excision.

摘要

12%的肾母细胞瘤患者肿瘤侵犯肾静脉,另有6%的患者肿瘤延伸至下腔静脉。在少数情况下,肿瘤可蔓延至心脏右侧。由于肾母细胞瘤患者很少需要进行肾动脉造影,且下腔静脉受累可能没有症状,因此在根治性肾切除术时才可能发现静脉侵犯。建议术前行腔静脉造影,若发现血栓,则需要进行右心造影以确定血栓的上界。了解肾的侧支静脉循环以及下腔静脉恶性或医源性梗阻的生理影响对于制定手术方案至关重要。各种手术操作、术中检查及手术辅助手段(包括体外循环和低温)已使腔内肾母细胞瘤能够被切除。

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