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两名患者对2型单纯疱疹病毒早期抗原的异常血清学反应。

Unusual serologic response to two patients to an early antigen of herpes simplex virus type 2.

作者信息

Arsenakis M, May J T

出版信息

Sex Transm Dis. 1982 Jul-Sep;9(3):143-5. doi: 10.1097/00007435-198207000-00010.

DOI:10.1097/00007435-198207000-00010
PMID:6293106
Abstract

Two patients infected with herpes simplex virus type 2 (HSV-2) who were free of recurrences over a 13-14-month period had an unusually high titer (greater than 1:48) of complement-fixing antibody to the early antigen (AG-4) of HSV-2. Their response was also unusual in that it was an IgG complement-fixing antibody rather than IgM, which normally is found in patients with HSV-2 infection. The antibody was also present 13-14 months after the episode of HSV-2 disease, whereas in other patients, the response had declined by six months.

摘要

两名感染2型单纯疱疹病毒(HSV-2)的患者在13至14个月期间未出现复发,其针对HSV-2早期抗原(AG-4)的补体结合抗体滴度异常高(大于1:48)。他们的反应也不寻常,因为这是一种IgG补体结合抗体,而非通常在HSV-2感染患者中发现的IgM。该抗体在HSV-2疾病发作13至14个月后仍存在,而在其他患者中,这种反应在六个月后就已下降。

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