Donoghue J P, Wise S P
J Comp Neurol. 1982 Nov 20;212(1):76-88. doi: 10.1002/cne.902120106.
The first motor (MI) cortex of the rat was identified as the region from which movements could be evoked by the lowest intensity of electrical stimulation. The location of this region was correlated with cytoarchitecture in the frontal and parietal cortex. Two frontal areas can be discerned in Nissl-stained sections: (1) the medial agranular field, marked by a pale-staining layer III and a compact layer II, and (2) the lateral agranular field, which has more homogeneous superficial layers and a broad layer V containing large, densely staining cells. Both of these regions project to the spinal cord and can therefore be included in the somatic sensorimotor cortex. MI in the rat coincides with the lateral agranular field but also overlaps with part of the adjacent granular cortex of the first somatic sensory (SI) representation. We conclude that the rat MI cortex can be identified by microstimulation techniques and by cytoarchitecture in the rat.
大鼠的第一运动（MI）皮层被确定为通过最低强度电刺激可诱发运动的区域。该区域的位置与额叶和顶叶皮层的细胞结构相关。在尼氏染色切片中可辨别出两个额叶区域：（1）内侧无颗粒区，其特征为浅染的III层和致密的II层；（2）外侧无颗粒区，其浅层更为均匀，V层较宽，含有大的、深染的细胞。这两个区域均投射至脊髓，因此可纳入躯体感觉运动皮层。大鼠的MI与外侧无颗粒区重合，但也与第一躯体感觉（SI）代表区相邻的部分颗粒皮层重叠。我们得出结论，大鼠的MI皮层可通过微刺激技术和细胞结构在大鼠中得以识别。
