Klemm W R, Sherry C J
Neurosci Biobehav Rev. 1982 Winter;6(4):429-37. doi: 10.1016/0149-7634(82)90026-4.
We suggest the possibility that neurons process information in terms of the relative duration of clusters of adjacent and successive inter-action potential intervals ("bytes" of intervals). If this concept is plausible, as is supported by research from several laboratories which have specifically addressed this possibility, one should be able to see evidence for such patterning in the published illustrations from studies in which this concept was not considered. We present some of this evidence here, along with some illustrations from the original publications. Byte patterns are evident in these examples, even though they went unrecognized by authors and readers alike. It is true that interval patterns are not obvious in all published illustrations of spike trains, and we suggest that this can be explained by one or more of the following: (1) some neurons may operate with an interval-pattern code while others do not, (2) a given neuron may use an interval-pattern code only under certain conditions, and (3) even when such a code exists, it may be difficult to detect for identifiable technical reasons. Therefore, we believe that the relative-internal-pattern concept is a valid scientific hypothesis which merits specific testing of its validity and range of applicability.
我们提出一种可能性，即神经元根据相邻和连续动作电位间隔簇的相对持续时间（间隔的“字节”）来处理信息。如果这一概念是合理的，正如几个专门研究过这种可能性的实验室的研究所支持的那样，那么在那些未考虑这一概念的研究发表的插图中，应该能够看到这种模式化的证据。我们在此展示一些此类证据，以及原始出版物中的一些插图。尽管作者和读者都未意识到，但字节模式在这些例子中是明显的。诚然，在所有已发表的尖峰序列插图中，间隔模式并不都明显，我们认为这可以由以下一个或多个原因来解释：（1）一些神经元可能使用间隔模式编码，而其他神经元则不然；（2）给定的神经元可能仅在某些条件下使用间隔模式编码；（3）即使存在这样的编码，由于可识别的技术原因，也可能难以检测到。因此，我们认为相对内部模式概念是一个有效的科学假设，值得对其有效性和适用范围进行具体测试。
