Salducci J, Planche D
Sem Hop. 1982 Oct 7;58(36):2097-100.
As the clinical manifestations of spasmophilia are characterized by their striking polymorphism, quantitative assessment, which is requisite in order to evaluate therapeutic effectiveness, is a difficult task. The authors have attempted to analyze clinical, electrical and biological data from 30 patients. Each of these patients, given only manganese-cobalt oligosol and magnesium oligosol for two months, in two daily doses, had at least two groups of symptoms. Analysis of results shows that the most significant improvement was clinical: improvement was satisfactory or very satisfactory in 83% of patients tested, with muscular relaxation being recorded first, In relation with these clinical results, is the 59% improvement rate in EMG controls. Improvement in overall laboratory data was conclusive in only 24% of patients; however, if only the changes in intraerythrocytic magnesium, which is the only parameter with real clinical value (60% of abnormal results before treatment) are considered, improvement or return to normal values was recorded in 83% of cases.
由于痉挛素质的临床表现具有显著的多态性，而定量评估是评估治疗效果所必需的，但这是一项艰巨的任务。作者试图分析30例患者的临床、电学和生物学数据。这些患者每人每天分两次服用锰钴低聚溶液和镁低聚溶液，持续两个月，均至少有两组症状。结果分析表明，最显著的改善是临床方面的：在83%接受测试的患者中，改善情况令人满意或非常令人满意，首先记录到肌肉松弛。与这些临床结果相关的是，肌电图检查的改善率为59%。总体实验室数据的改善仅在24%的患者中具有决定性意义；然而，如果仅考虑红细胞内镁含量的变化（这是唯一具有实际临床价值的参数，治疗前60%的结果异常），则83%的病例中该指标得到改善或恢复到正常水平。
