一名急性淋巴细胞白血病患儿的组织细胞性髓性网状细胞增多症样综合征完全康复。

Complete recovery of histiocytic medullary reticulosis-like syndrome in a child with acute lymphoblastic leukemia.

作者信息

Yin J A, Kumaran T O, Marsh G W, Rossiter M, Catovsky D

出版信息

Cancer. 1983 Jan 15;51(2):200-2. doi: 10.1002/1097-0142(19830115)51:2<200::aid-cncr2820510204>3.0.co;2-c.

DOI:10.1002/1097-0142(19830115)51:2<200::aid-cncr2820510204>3.0.co;2-c

Abstract

A 6-year-old boy with acute lymphoblastic leukemia (ALL) developed a haemophagocytic syndrome resembling histiocytic medullary reticulosis (HMR) but made a complete recovery on supportive treatment. This was subsequently found to have been associated with a parainfluenzal infection. It is suggested that HMR in immunocompromised hosts may represent a reactive process to an opportunistic viral infection and that the use of chemotherapy in these patients may be deleterious.

摘要

一名6岁急性淋巴细胞白血病（ALL）男孩发生了类似组织细胞性髓性网状细胞增生症（HMR）的噬血细胞综合征，但经支持治疗后完全康复。随后发现这与副流感病毒感染有关。提示免疫功能低下宿主中的HMR可能是对机会性病毒感染的一种反应性过程，且在这些患者中使用化疗可能有害。