Separation of viral DNA molecules in horizontal agarose slab gels using a new type of wick.

A new type of rayon fiber wick was used to establish uniform electrical paths between agarose slab gels and the electrodes of a horizontal electrophoresis apparatus. Separation of viral DNA molecules, either digested with restriction enzymes or relaxed with eukaryotic topoisomerases, was achieved easily at both low and relatively high voltage.