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水泡性口炎病毒可在叙利亚仓鼠中建立持续性感染。

Vesicular stomatitis virus can establish persistent infections in Syrian hamsters.

作者信息

Fultz P N, Shadduck J A, Kang C Y, Streilein J W

出版信息

J Gen Virol. 1982 Dec;63(2):493-7. doi: 10.1099/0022-1317-63-2-493.

DOI:10.1099/0022-1317-63-2-493
PMID:6296291
Abstract

Persistent infections by vesicular stomatitis virus (VSV) of the Indiana serotype were readily established in adult Syrian hamsters following intraperitoneal injection of the virus. Plaque-forming virus, identified as VSV by serological and physical criteria, was isolated from brain homogenates of five hamsters that were tested 3 to 8 months after infection. Four of these animals had exhibited either transient or permanent paralysis, whereas the fifth appeared healthy, during the period of observation. At the time of sacrifice all hamsters had high titres of anti-VSV-neutralizing antibodies in their sera.

摘要

腹腔注射印第安纳血清型水泡性口炎病毒(VSV)后,成年叙利亚仓鼠很容易建立起该病毒的持续性感染。通过血清学和物理标准鉴定为VSV的噬斑形成病毒,从感染后3至8个月接受检测的5只仓鼠的脑匀浆中分离出来。在观察期内,其中4只动物表现出短暂或永久性麻痹,而第5只看起来健康。在处死时,所有仓鼠血清中都有高滴度的抗VSV中和抗体。

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Vesicular stomatitis virus can establish persistent infections in Syrian hamsters.水泡性口炎病毒可在叙利亚仓鼠中建立持续性感染。
J Gen Virol. 1982 Dec;63(2):493-7. doi: 10.1099/0022-1317-63-2-493.
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