脑啡肽可提高苹果螺中多巴胺能传递的效能。
Enkephalin increases the efficacy of dopaminergic transmission in Helix pomatia.
作者信息
Juel C
出版信息
Neuropharmacology. 1982 Dec;21(12):1301-3. doi: 10.1016/0028-3908(82)90137-x.
PMID:6296715
Abstract
A dopaminergic synaptic connection in Helix pomatia was studied. Transmitter mobilization was measured during incubation with met-enkephalin. Enkephalin decreased the time constant for transmitter mobilization. The effect was blocked by naloxone. It is postulated that the presynaptic cell possesses opiate receptors and that these receptors mediate the enkephalin-induced increase in efficacy of dopaminergic transmission.
摘要
对苹果螺中的多巴胺能突触连接进行了研究。在与甲硫氨酸脑啡肽一起孵育期间测量递质动员情况。脑啡肽缩短了递质动员的时间常数。该效应被纳洛酮阻断。据推测，突触前细胞具有阿片受体，且这些受体介导脑啡肽诱导的多巴胺能传递效能增加。
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