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皮肤良性纤维组织细胞瘤。290例形态学研究。

Benign fibrous histiocytoma of the skin. A morphologic study of 290 cases.

作者信息

Gonzalez S, Duarte I

出版信息

Pathol Res Pract. 1982 Oct;174(4):379-91. doi: 10.1016/S0344-0338(82)80019-8.

Abstract

Two hundred and ninety cases of benign fibrous histiocytoma of the skin are reviewed. Their frequency, distribution according to age, sex and sites, and the architectural and cytological features of the tumors are analyzed. Ninety two cases (31,7%) were male and 198 cases (68,3%) were female. The tumors were most frequently found between second and fourth decades and located mainly in the extremities. Twenty three cases were clinically diagnosed as malignant tumors. Five cytological patterns of benign fibrous histiocytoma of the skin are described: fibrous, vascular, xanthomatous, pleomorphic and giant cell histiocytoma. Their probable histogenesis and the spectrum of morphological variants are discussed.

摘要

本文回顾了290例皮肤良性纤维组织细胞瘤。分析了其发病率、按年龄、性别和部位的分布情况,以及肿瘤的结构和细胞学特征。92例(31.7%)为男性,198例(68.3%)为女性。肿瘤最常见于第二至第四个十年,主要位于四肢。23例临床诊断为恶性肿瘤。描述了皮肤良性纤维组织细胞瘤的五种细胞学模式:纤维型、血管型、黄色瘤型、多形性和巨细胞组织细胞瘤型。讨论了它们可能的组织发生及形态学变异谱。

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