Handler S
Postgrad Med. 1983 Feb;73(2):301-7. doi: 10.1080/00325481.1983.11697775.
Most of the serious organic diseases of the colon are etiologically linked to the high-saturated-fat and low-fiber Western diet. Benign but common conditions, such as appendicitis and diverticular disease of the colon, appear to be due to deficiency of fiber and attendant low-bulk stools. Colon cancer appears to be due to carcinogens created in the colon itself. Contributing to carcinogen production are cocarcinogens in bile and an increase in anaerobic bacteria, both directly related to high levels of saturated fat in the diet. If these common disorders of the colon are to be controlled, our diet will require major modification. Changes will have to include reduction of saturated fats of animal origin and increase in cereal grains.
结肠的大多数严重器质性疾病在病因上与西方高饱和脂肪、低纤维饮食有关。一些良性但常见的病症,如阑尾炎和结肠憩室病,似乎是由于纤维缺乏以及随之而来的粪便量少所致。结肠癌似乎是由结肠自身产生的致癌物引起的。胆汁中的辅致癌物和厌氧菌的增加促成了致癌物的产生,这两者都与饮食中高水平的饱和脂肪直接相关。如果要控制这些常见的结肠疾病,我们的饮食将需要进行重大调整。调整必须包括减少动物源性饱和脂肪的摄入并增加谷物的摄入。