Blakeley A G, Cunnane T C
Q J Exp Physiol. 1982 Oct;67(4):617-28. doi: 10.1113/expphysiol.1982.sp002681.
The effects of cooling upon the excitatory junction potential (e.j.p.) and spontaneous e.j.p.s. in the guinea-pig vas deferens have been studied. A series of strict criteria have been used to select 'successful' penetration of smooth muscle cells by the micro-electrodes. Cooling the vas from 35 to 22 degrees C has little effect on the membrane potential. The e.j.p. is increased in size by cooling from 5 . 1 +/- 0.2 mV, n = 120 at 35 degrees C to 15 . 9 +/- 0 . 5 mV, n = 29 at 22 degrees C. Facilitation is less marked at lower temperatures. The effects of cooling are not due to any effects under the electrodes used to stimulate the innervation of the vas. The frequency and size of spontaneous e.j.p.s. is reduced by cooling. The significance of these observations is discussed.
研究了冷却对豚鼠输精管兴奋性接头电位（e.j.p.）和自发性e.j.p.s的影响。已采用一系列严格标准来选择微电极对平滑肌细胞的“成功”刺入。将输精管从35℃冷却至22℃对膜电位影响不大。e.j.p.的大小通过冷却从35℃时的5.1±0.2mV（n = 120）增加到22℃时的15.9±0.5mV（n = 29）。在较低温度下易化作用不太明显。冷却的影响并非由于用于刺激输精管神经支配的电极下方的任何效应所致。冷却会降低自发性e.j.p.s的频率和大小。讨论了这些观察结果的意义。
