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体外海马组织的氧毒性

Oxygen toxicity of hippocampal tissue in vitro.

作者信息

King G L, Parmentier J L

出版信息

Brain Res. 1983 Jan 31;260(1):139-42. doi: 10.1016/0006-8993(83)90775-8.

Abstract

The effects of hyperbaric oxygen have been studied on synaptic transmission in the hippocampal brain slice. Oxygen enhances both the prevolley and postsynaptic potential of extracellularly recorded responses following focal stimulation of afferent fiber bundles, but synaptic efficiency is reduced. It is suggested that hyperbaric oxygen causes changes in potassium distribution in the slice.

摘要

高压氧对海马脑片突触传递的影响已得到研究。在对局灶性刺激传入纤维束后细胞外记录的反应中,氧增强了峰电位前和突触后电位,但突触效率降低。提示高压氧导致脑片中钾分布发生变化。

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