Kaaber K, Veien N K, Tjell J C
Br J Dermatol. 1978 Feb;98(2):197-201. doi: 10.1111/j.1365-2133.1978.tb01622.x.
Of 28 patients with chronic nickel dermatitis 17 experienced aggravation following oral ingestion of 2.5 mg nickel, but not a placebo tablet. The dermatitis of 9 of the 17 patients improved during a period of 6 weeks on a low nickel diet. The dermatitis of 7 of the 9 patients flared again when a normal diet was resumed. Nickel excretion over a 24-h period was measured for 14 of the 17 patients by atomic absorption spectrophotometry before, during, and after the diet. Reduced excretion was seen during the diet with no statistically significant difference between patients whose dermatitis improved during the diet and those whose dermatitis showed no change.
在28例慢性镍皮炎患者中，17例在口服2.5毫克镍后病情加重，而服用安慰剂片则无此情况。17例患者中有9例在低镍饮食6周期间皮炎有所改善。9例患者中有7例在恢复正常饮食后皮炎再次发作。通过原子吸收分光光度法对17例患者中的14例在饮食前、饮食期间和饮食后测量了24小时的镍排泄量。饮食期间排泄量减少，饮食期间皮炎改善的患者与皮炎无变化的患者之间无统计学显著差异。
