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天疱疮细胞间抗体的致病性及其通过血浆置换从循环中定期清除。

Pathogenicity of the intercellular antibodies of pemphigus and their periodic removal from the circulation by plasmapheresis.

作者信息

Ruocco V, Rossi A, Argenziano G, Aatarita C, Alviggi L, Farzati B, Papaleo G

出版信息

Br J Dermatol. 1978 Feb;98(2):237-41. doi: 10.1111/j.1365-2133.1978.tb01630.x.

Abstract

The authors are convinced that the intercellular antibodies of pemphigus are pathogenic. Consequently periodic plasmapheresis in two patients with pemphigus has been performed to remove the antibodies from the circulation. After larger plasma-exchanges there was a decrease of the antibody titre and a parallel improvement of the clinical condition.

摘要

作者确信天疱疮的细胞间抗体具有致病性。因此,对两名天疱疮患者进行了定期血浆置换,以从循环中清除抗体。在进行较大规模的血浆置换后,抗体滴度降低,临床状况同时得到改善。

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