Sandyk R
S Afr Med J. 1983 Feb 26;63(9):323-5.
The Eaton-Lambert syndrome is a non-metastatic manifestation of oat-cell carcinoma of the bronchus, although it has been reported in patients with carcinoma at other sites. The clinical picture is usually one of subacute muscular fatiguability with weakness and wasting affecting the proximal parts of the limbs and trunk, but occasionally the external ocular and bulbar muscles are involved. The weakness is often myasthenic, but it has been observed that muscle power may in fact increase after brief exercise. The pathogenesis, diagnosis, electrophysiological features and some aspects of therapy are reviewed.
伊顿-兰伯特综合征是支气管燕麦细胞癌的一种非转移性表现,尽管在其他部位患有癌症的患者中也有报道。临床表现通常是亚急性肌肉易疲劳,伴有影响四肢和躯干近端的无力和消瘦,但偶尔也会累及眼外肌和延髓肌。肌无力通常类似重症肌无力,但据观察,短暂运动后肌肉力量实际上可能会增强。本文对其发病机制、诊断、电生理特征及治疗的一些方面进行了综述。