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因遮盖疗法导致的弱视:对单眼或双眼使用阿托品饲养的小猫的神经生理学研究。

Amblyopia resulting from penalisation: neurophysiological studies of kittens reared with atropinisation of one or both eyes.

作者信息

Ikeda H, Tremain K E

出版信息

Br J Ophthalmol. 1978 Jan;62(1):21-28. doi: 10.1136/bjo.62.1.21.

Abstract

Atropinisation of the eyes--a clinical method of treating strabismus called "penalisation"--in developing kittens caused a reduction in the spatial resolving power of cells in the lateral geniculate nucleus driven by the penalised eye, regardless of whether 1 eye or both eyes had been atropinised. However, binocularity of cells in the visual cortex was reduced only in monocularly penalised cats. It appears that sharply focused foveal images are important in the development of good visual acuity but synergy of the inputs to the 2 eyes is required for the development of binocular vision.

摘要

在发育中的小猫身上,对眼睛进行阿托品化处理——一种名为“抑制疗法”的斜视临床治疗方法——会导致外侧膝状核中由被抑制眼睛驱动的细胞的空间分辨能力下降,无论被阿托品化的是一只眼睛还是两只眼睛。然而,只有在单眼被抑制的猫中,视觉皮层中细胞的双眼性才会降低。看来,清晰聚焦的中央凹图像对良好视力的发育很重要,但双眼视觉的发育需要双眼输入的协同作用。

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本文引用的文献

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Experimental analysis of amblyopia and strabismus.弱视与斜视的实验分析
Br J Ophthalmol. 1974 Mar;58(3):176-82. doi: 10.1136/bjo.58.3.176.
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Factors involved in the production of amblyopia.弱视产生的相关因素。
Br J Ophthalmol. 1974 Mar;58(3):158-64. doi: 10.1136/bjo.58.3.158.

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