Ilancheran A, Ratnam S S
Ann Acad Med Singap. 1982 Oct;11(4):539-44.
What was once an almost uniformly fatal disease has now become highly curable, with survival rates of 100% being reported for the early stages of the disease. This is the direct result of improved techniques of diagnosis, recognition of high risk groups, effective and intensive chemotherapy, adjunctive surgery in selected cases and most important of all, a close follow-up of all patients with monitoring of the tumour marker, human chorionic gonadotrophin (hCG). This review will highlight the advances made in these areas and how these have helped in reducing morbidity and mortality from gestational trophoblastic disease (GTD).
曾经几乎是一种必死无疑的疾病，如今已变得极易治愈，据报道该疾病早期的生存率可达100%。这是诊断技术改进、高危人群识别、有效且强化化疗、特定病例辅助手术以及最重要的——对所有患者进行密切随访并监测肿瘤标志物人绒毛膜促性腺激素（hCG）的直接结果。本综述将重点介绍这些领域取得的进展，以及它们如何有助于降低妊娠滋养细胞疾病（GTD）的发病率和死亡率。
