Hamilton D N, Ledger V, Diamandopoulos A
Lancet. 1976 Nov 27;2(7996):1170-1. doi: 10.1016/s0140-6736(76)91683-4.
A dinitrochlorobenzene (D.N.C.B.)/red-blood-cell conjugate inhibited migration of leucocytes which came from D.N.C.B. sensitised patients. This effect provided the basis for a rapid, sensitive, and quantitative in-vitro measure of D.N.C.B. sensitivity. Frequent serial measurement of cell-mediated immunity was possible with the test, provided D.N.C.B. sensitivity was maintained by occasional skin patch tests.
二硝基氯苯(D.N.C.B.)/红细胞结合物可抑制来自D.N.C.B.致敏患者的白细胞迁移。这一效应为快速、灵敏且定量地体外测定D.N.C.B.敏感性提供了基础。如果通过偶尔的皮肤斑贴试验维持D.N.C.B.敏感性,那么该试验就能够对细胞介导免疫进行频繁的系列测量。