Hogg R J, Arant B S, Houser M T
Int J Pediatr Nephrol. 1982 Dec;3(4):287-91.
The management, complications and outcome of two small children who developed Candida albicans peritonitis are reported. Both children developed peritonitis while on continuous ambulatory peritoneal dialysis (CAPD) but their fungal infections were treated differently. In one patient, Amphotericin B (1-4 micrograms/ml) was added to the dialysate; infection resolved but an extensive fibrous reaction developed in the peritoneal cavity making subsequent CAPD ineffective. The second patient was treated with a recently introduced oral antifungal agent, Ketoconazole; her catheter was removed. This patient recovered without any identifiable side effects of the drug. This report discusses the clinical course of two different approaches to Candida peritonitis and suggests certain recommendations regarding the treatment of this uncommon, but potentially lethal complication of CAPD.
报告了两名患白色念珠菌性腹膜炎幼儿的治疗、并发症及转归情况。两名患儿均在持续非卧床腹膜透析（CAPD）期间发生腹膜炎，但对其真菌感染的治疗方法不同。一名患者在透析液中加入两性霉素B（1 - 4微克/毫升）；感染得到解决，但腹腔内出现广泛的纤维反应，导致后续CAPD无效。第二名患者接受了最近引入的口服抗真菌药物酮康唑治疗；其导管被拔除。该患者康复且未出现该药物任何可识别的副作用。本报告讨论了针对念珠菌性腹膜炎的两种不同治疗方法的临床过程，并就这种CAPD罕见但可能致命的并发症的治疗提出了某些建议。
