Lee S H, Chiang S S, Hseih S J, Shen H M
Department of Medicine, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan, People's Republic of China.
Adv Perit Dial. 1995;11:172-5.
Two patients who developed fungal peritonitis after receiving continuous ambulatory peritoneal dialysis (CAPD) for various periods were successfully treated with intracatheter retention of amphotericin B 1-2 mg and oral flucytosine or fluconazole 50 mg b.i.d. for 5 weeks. The catheter was not removed and efficient peritoneal permeability was maintained. We suggest that intracatheter retention of antifungal agents to sterilize the catheter with simultaneous oral antifungal agents be used to eradicate peritoneal infection. The catheter may not have to be removed, and CAPD can be accomplished. Period of hospitalization may be shortened, and the efficiency of CAPD can be maintained.
两名在接受不同时长的持续性非卧床腹膜透析（CAPD）后发生真菌性腹膜炎的患者，通过在导管内留置1 - 2毫克两性霉素B并口服50毫克氟胞嘧啶或氟康唑，每日两次，持续5周，成功得到治疗。导管未被拔除，且维持了有效的腹膜通透性。我们建议采用在导管内留置抗真菌药物以对导管进行消毒，同时口服抗真菌药物的方法来根除腹膜感染。导管可能无需拔除，CAPD仍可继续进行。这样可以缩短住院时间，并维持CAPD的有效性。
